Regeneration of endogenous myocardial tissue by induction of neovascularization

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专利权人:

The Trustees of Columbia University

发明人:

Itescu, Silviu

申请号：

AU2009213032

公开号：

AU2009213032B2

申请日:

2009.09.10

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2009213032B220130627.pdf#####ABSTRACT This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which 5 comprises administering to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the subject's heart so as to thereby treat the disorder. This invention further provides the instant method wherein the agent is human endothelial progenitor 10 cells, G-CSF, GM-CSF, SDF-1, and IL-8. This invention also provides methods of determining the susceptibility of a cardiomyocyte in a subject to apoptosis.

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