Facchini, Peter James,Chen, Xue,Dang, Thi Thu Thuy
申请号:
AU2014306345
公开号:
AU2014306345B2
申请日:
2014.08.15
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Methods for the manufacture of the therapeutic chemical compound noscapine and noscapine synthesis intermediates comprising contacting a noscapine pathway precursor selected from a first canadine derivative, a first papaveroxine derivative and narcotine hemiacetal with at least one of the enzymes selected from the group CYP82Y1, CYP82X1, AT1, CYP82X2, OMT, CXE1 and NOS.