Combination preparation and pharmaceutical composition are described, it is included:(a) albumen of LAG 3 that can be combined with MHC II quasi-molecules or derivatives thereof;Apoptosis albumen 1 (PD 1) pathway inhibitor (b).The pathway inhibitors of PD 1, such as anti-the antibody of PD 1 or anti-PD L1 antibody, and serve as the LAG 3 of APC activators soluble derivative cooperate with together activating T cell (particularly CD8+T cell).Combination preparation and composition are described as medicine, it is especially useful in treating cancer or the purposes of infection, and for treating cancer or the method for infection.Mevcut buluş birleşik preparasyonlar ve farmasötik bileşimlerle ve bunların ilaç olarak, özellikle de kanser veya enfeksiyon tedavisine yönelik olarak kullanımlarıyla ilgilidir. Kanser veya enfeksiyon tedavisine yönelik metotlar da ayrıca tarif edilmektedir.