The present invention provides a silatrane-containing zwitterionic material and an antifouling substrate including the same, wherein the silatrane-containing zwitterionic material has a structure of formula (I): wherein Zt- is R7-SO3-, R7-CO2-, R7-OPO32-, R7-PO32-, R7-OP(=O)(R)O-, the structure of R1, R2, R3, R7 are independently selected from the group consisting of an aliphatic group, an aromatic group, a branched chain group, a straight chain group, a cyclic group and a heterocyclic group； and R4, R5 and R6 are independently selected from the group consisting of a methyl group, H, an ethyl group, and CH2Cl. The present invention further provides an antifouling substrate including a base layer and a coated layer, wherein the base layer has a hydroxyl group-containing surface, and the coated layer is formed by coating a silatrane-containing zwitterionic material on the hydroxyl group-containing surface to form Si-O-Si bonds between the silatrane-containing zwitterionic material and the base layer and sequentially grafted to the base layer.本發明提供一種帶有氮矽三環的兩性雙離子材料以及包含該材料之抗汙基材，其中，該帶有氮矽三環的兩性雙離子材料具有式(I)之結構： 。
