ARMANI, ELISABETTA,CAPALDI, CARMELIDA,JENNINGS, ANDREW STEPHEN ROBERT,HEALD, ROBERT ANDREW,SUTTON, JONATHAN MARK
申请号：
ARP170101444
公开号：
AR108610A1
申请日:
2017.05.26
申请国别(地区):
AR
年份:
2018
代理人:
摘要：
Claim 1: wherein is a compound of formula (1) or a pharmaceutically acceptable Salt thereof,Where is selected from the group consisting of the remains of a group of formulas (2),Where the nitrogen Atom is designated by the Asterisk * 4 - cianofenilo joined the group and the carbon Atom with # Care is attached to the carbon atom of the Ring 2 - oxo - 23 - dihidroimidazol； X is selected from the group consisting of the remains of a group of formula (3),Or is selected from the group consisting of compounds of formula (4) and (5)； r u00b9 is selected from the group consisting of the remains of a group of formulas (6)； n is an integer between 1 and 4 m；Is 0 or an integer between 1 and 4； t is 0 or an integer between 1 and 4； and is an integer between 1 and 4； W is an integer between 1 and 4； Z is 0 OR 1； R is 0 OR 1； R u00b2 is - H OR - c u2081 u208b u2084 linear or branched alkyl r u00b3； - c u2081 u208b u2084R u00b2 linear or branched alkyl or cycloalkyl together and can form a r u00b3； r u2074 is selected from the group consisting arilen c u2081 u208b u2084 Rent nr u1d48r u1d49 - - - - - - c u2081 u208b u2084 rent, arilen n u207ar u1d43r u1d47r u1d9c,Heteroarilen c u2081 u208b u2084 Rent - - - - - nr u1d48r u1d49, heteroarilen c u2081 u208b u2084 Rent - n u207ar u1d43r u1d47r u1d9c and heteroaryl, where any such arilen c u2081 u208b u2084 Rent - - - - nr u1d48r u1d49, arilen c u2081 u208b u2084 Rent - n u207ar u1d43r u1d47r u1d9c,- heteroarilen - c u2081 u208b u2084 Rent - nr u1d48r u1d49,- heteroarilen - c u2081 u208b u2084 Rent - n u207ar u1d43r u1d47r u1d9c and heteroaryl can be optionally substituted with one or more alkyl - or c u2081 u208b u2084 r u2074 is selected from the group consisting of the remains of a group of formulas(7)； r u2075 is selected from the group consisting c u2081 u208b u2084 alquilenoxi - aryl (or alkyl, c u2081 u208b u2084 OC) - NH - linear or branched, u209c n u207ar u1d43r u1d47r u1d9c - (ch u2082) -, - C (o) - N - (r u00b9 u2070) c u20
