Bruce Molitoris;Shai Erlich;Elena Feinstein;Svetlana Adamsky
发明人:
Elena Feinstein,Svetlana Adamsky,Shai Erlich,Bruce Molitoris
申请号：
US13376766
公开号：
US08637482B2
申请日:
2010.06.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to methods for treating chronic kidney disease (CKD) including methods for preventing or delaying onset of CKD and methods for preventing exacerbation and progression of CKD. In particular embodiments, the invention provides methods for treating a subject at risk of developing CKD comprising administering to the subject a composition comprising a) a therapeutically effective amount of at least one oligonucleotide compound which inhibits the expression of a human target gene associated with the kidney disease； and b) a pharmaceutically acceptable excipient or carrier, or mixtures thereof, thereby reducing the risk of CKD in the subject.
