The University of Queensland;The University of Adelaide;Griffith University
发明人:
申请号:
EP18867181.2
公开号:
EP3694515A1
申请日:
2018.10.12
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
This invention relates to the use of zinc(II) salts in combination with a zinc ionophore to resensitize a previously resistant pathogenic bacteria to an antibiotic. Methods of restoring the sensitivity of a resistant pathogenic bacterium to an antibiotic comprising administering a zinc ionophore in combination with a zinc(II) salt and methods of treating a bacterial infection comprising administering a zinc ionophore in combination with a zinc (II) salt concurrently and/or sequentially with administration of a therapeutically effective amount of an antibiotic is also described.