THE UNIVERSITY OF QUEENSLAND;THE UNIVERSITY OF ADELAIDE;GRIFFITH UNIVERSITY
发明人:
Mark WALKER,Christopher MCDEVITT,Mark VON ITZSTEIN,Alastair MCEWAN
申请号：
US16755328
公开号：
US20200261440A1
申请日:
2018.10.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This invention relates to the use of zinc(II) salts in combination with a zinc ionophore to resensitize a previously resistant pathogenic bacteria to an antibiotic. Methods of restoring the sensitivity of a resistant pathogenic bacterium to an antibiotic comprising administering a zinc ionophore in combination with a zinc(II) salt and methods of treating a bacterial infection comprising administering a zinc ionophore in combination with a zinc (II) salt concurrently and/or sequentially with administration of a therapeutically effective amount of an antibiotic is also described.
