SCHWARZ, MATTHIAS,GAILLARD, PASCALE,GOTTELAND, JEAN-PIERRE,THOMAS, RUSSELL J.,PAGE, PATRICK
申请号：
CA2524161
公开号：
CA2524161C
申请日:
2004.05.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention is related to pyridinyl acetonitriles of formula (Ia),(Ib), and(Ic)(see formula Ia)(see formula Ib)(see formula Ic)as well as to pharmaceutical formulations containing such pyridinylacetonitriles.Said pyridinyl acetonitriles are modulators of the protein kinase signalingpathways, particularly the one involving Glycogen Kinase Synthase 3 or JNK.Thepresent invention is furthermore related to methods of preparing pyridinylacetonitriles. X is a substituted or unsubstituted pyridinyl. G is anunsubstituted orsubstituted pyrimidinyl or triazinyl.
