Gary J. Nabel,Bimal Chakrabarti,Wing-Pui Kong,Yue Huang,Zhi-Yong Yang,Jason G. D. Gall,C. Richter King
申请号:
US13086884
公开号:
US08323961B2
申请日:
2011.04.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a composition comprising four adenoviral vectors, each comprising a nucleic acid sequence encoding a clade A HIV Env protein, a clade B HIV Env protein, a clade C HIV Env protein, and a clade B HIV Gag-Pol fusion protein, respectively. The invention also provides a method of inducing an immune response against HIV-1 in an animal comprising administering the composition to the animal.