您的位置: 首页 > 农业专利 > 详情页

Prodrugs of smokers and their use in the treatment of various diseases
专利权人:
Alkermes Pharma Ireland Limited
发明人:
ZEIDAN, Tarek,DUNCAN, Scott,HENCKEN, Christopher,WYNN, Thomas,SANRAME, Carlos
申请号:
ES14767892
公开号:
ES2683355T3
申请日:
2014.03.14
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A compound of Formula (III), or a pharmaceutically acceptable salt thereof: ** Formula ** wherein: ** Formula ** R1 is unsubstituted C1-C6 alkyl; R6, R7, R8 and R9 are each, independently, H, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C2-C6 alkenyl, substituted or unsubstituted C2-C6 alkynyl or C (O) ORa; Ra is H or substituted or unsubstituted C1-C6 alkyl; m is 0, 1, 2 or 3; t is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10; and each R10 is independently H, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C2-C6 alkenyl, substituted or unsubstituted C2-C6 alkynyl, substituted or unsubstituted C3-C10 carbocycle, substituted heterocycle or unsubstituted comprising one or two rings of 5 or 6 members and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two rings of 5 or 6 members and 1-4 heteroatoms selected from N, O and S; or, alternatively, two R10 anchored to the same carbon atom, together with the carbon atom to which they are attached, form a carbonyl, substituted or unsubstituted C3-C10 carbocycle, substituted or unsubstituted heterocycle comprising one or two rings of 5 or 6 members and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two rings of 5 or 6 members and 1-4 heteroatoms selected from N, O and S; or, alternatively, two R10 anchored to different atoms, together with the atoms to which they are attached, form a substituted or unsubstituted C3-C10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5 or 6 member rings and 1 -4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two rings of 5 or 6 members and 1-4 heteroatoms selected from N, O and S.Un compuesto de Fórmula (III), o una sal farmacéuticamente aceptable del mismo:**Fórmula** en donde:**Fórmula** R1 es alquilo C1-C6 no sustituido; R6, R7, R8 y R9 son cada uno, independ
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充