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Methods of mitigating effects of radiation and reducing the risk of systemic infection
专利权人:
The University of Texas System;The Board of Regents
发明人:
Carney, Darrell
申请号:
AU2011265228
公开号:
AU2011265228A1
申请日:
2011.06.10
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention is directed to methods of reducing mortality in a subject exposed to a lethal dose of radiation comprising administering to the subject an effective amount of a thrombin peptide derivative described herein. Also included are methods of reducing the risk of developing bacterial, fungal or viral systemic infection a subject who is exposed or not exposed to radiation, methods of treating a subject with traumatic injury, dermal injury and/or bum injury who is also exposed to radiation, methods of reducing radiation related injury in a subject undergoing radiation therapy, methods of reducing the risk of developing a radiation induced illness, and methods of promoting the healing of a wound that is caused by radiation exposure and/or has been exposed to radiation. These methods comprising administering to the subject an effective amount of a thrombin peptide derivative described herein.
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