President and Fellows of Harvard College;Metro International Biotech, LLC
发明人:
David A. SINCLAIR,Jun Li,Karl D. Normington
申请号：
US16475832
公开号：
US20190350960A1
申请日:
2018.01.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides methods of modulating and regulating NHD protein-protein interactions through nicotinamide mononucleotide, analogs and derivatives thereof, such as NAD+. Such modulation may be useful in methods of treating and preventing cancer, aging, cell death, radiation damage, radiation exposure, among others, may improve DNA repair, cell proliferation, cell survival, among others, and may increase the life span of a cell or protect it against certain stresses, among others
