The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
Peter D. Kwong,Gary J. Nabel,Rebecca S. Rudicell,John Mascola,Mark Connors,Ivelin Georgiev,Jiang Zhu,Young Do Kwon,Tongqing Zhou,Yongping Yang,Baoshan Zhang,Gwo-Yu Chuang,Xueling Wu,Zhi-yong Yang,Wei
申请号:
US14363740
公开号:
US09695230B2
申请日:
2012.12.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Monoclonal neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed.