THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
KWONG, PETER D.,NABEL, GARY J.,RUDICELL, REBECCA S.,MASCOLA, JOHN R.,CONNORS, MARK,GEORGIEV, IVELIN,ZHU, JIANG,KWON, YOUNG DO,ZHOU, TONGQING,YANG, YONGPING,ZHANG, BAOSHAN,CHUANG, GWO-YU,WU, XUELING,YA
申请号：
CA2858716
公开号：
CA2858716A1
申请日:
2012.12.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Monoclonal neutralizing antibodies that specifically bind to HIV-1 gpl20 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed.
