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METHODS AND APPARATUS FOR THE CVCS
专利权人:
发明人:
DYER GORDON
申请号:
IN388/MUMNP/2014
公开号:
IN2014MN00388A
申请日:
2014.03.01
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The present invention provides an indirect method and accompanying apparatus for supplying a high concentration of medicaments particularly antibiotics to the nasal sinuses by first loading the medicament into the cerebrospinal venous system (CVCS) via a Valsalva manuever. Because the CVCS is a valveless three dimensional closed system traditional physiological dogma such as veins always draining tissues does not always apply. Instead because in its closed system blood can flow in any direction the blood of the CVCS and any medicaments that it contains will be drawn to any portion of it where there is increased outflow such as the copious venousderived sinus fluid drainage present during nasal allergy or nasal infection. Thus the very nasal congestion that impedes the effectiveness of direct medicament application such as seen with nasal inhalers or systemic antibiotics aids in applying the medicament indirectly to the nasal sinuses via the CVCS. Additionally the present method has the benefit of delivering medicaments that unlike present treatment regimens are not limited solely to those medicaments that can be successfully absorbed from the G.I. tract. This means that in the case of antibiotics the bacteria infecting this portion of the CVCS will not be as resistant to treatment if they have not had prior exposure to this new line of antibiotics. Finally if the infection extends to the eardrums making the Valsalva maneuver painful or if the patient is simply unusually sensitive then earplugs to reduce the stress on the eardrums may be worn while the patient performs the Valsalva maneuver.
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