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COMPOSE PHENYL TETRAHYDROISOQUINOLEINE SUBSTITUE PAR UN HETEROARYLE
专利权人:
LTD.;TAISHO PHARMACEUTICAL CO.
发明人:
KURODA, SHOICHI,KAWABE, KENICHI,USHIKI, YASUNOBU,OHTA, HIROSHI,UNEUCHI, FUMITO,SHIBATA, TSUYOSHI,TABUSE, HIDEAKI,MUNETOMO, EIJI,CHONAN, SUMI
申请号:
CA2955572
公开号:
CA2955572A1
申请日:
2015.07.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided is a compound represented by formula [1] that has excellent NHE3 inhibitory effects, or a pharmaceutically acceptable salt thereof. (In formula [1], A indicates a structure represented by formula [2]. In formula [2], R11 and R12 represent a halogen atom or the like, R2 indicates a C1-6 alkyl or the like, ring E indicates a triazole, a tetrazole, a pyrimidine or the like, R31 and R32 represent a hydrogen atom, a C1-6 alkyl, a C1-6 alkoxy or the like, and W indicates a single bond, a formula NH, a formula O, or a formula CONH. Y indicates a hydrogen atom or a structure represented by formula [3'].)
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