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PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL
专利权人:
Taisho Pharmaceutical Co.; Ltd.
发明人:
KURODA, Shoichi,KAWABE, Kenichi,USHIKI, Yasunobu,OHTA, Hiroshi,UNEUCHI, Fumito,SHIBATA, Tsuyoshi,TABUSE, Hideaki,MUNETOMO, Eiji,CHONAN, Sumi
申请号:
EP15825310
公开号:
EP3173408A4
申请日:
2015.07.24
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof which has an excellent NHE3 inhibitory effect: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ[Formula 15]€ƒ€ƒ€ƒ€ƒ€ƒA-Y [1] wherein A represents a structure represented by the following formula [2]: wherein R 11 and R 12 each represent a halogen atom or the like, R 2 represents C 1-6 alkyl or the like, ring E represents triazole, tetrazole, pyrimidine, or the like, R 31 and R 32 each represent a hydrogen atom, C 1-6 alkyl, C 1-6 alkoxy, or the like, and W represents a single bond, the formula -NH-, the formula -O-, or the formula -CONH-, and Y represents a hydrogen atom or a structure represented by the following formula [3]:
来源网站:
中国工程科技知识中心
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