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COMPOSTO DE FENIL TETRA-HIDROISOQUINOLINA SUBSTITUÍDO COM HETEROARILO
专利权人:
TAISHO PHARMACEUTICAL CO.; LTD.
发明人:
SHOICHI KURODA,KENICHI KAWABE,YASUNOBU USHIKI,HIROSHI OHTA,FUMITO UNEUCHI,TSUYOSHI SHIBATA,HIDEAKI TABUSE,EIJI MUNETOMO,SUMI CHONAN
申请号:
PT15825310
公开号:
PT3173408T
申请日:
2015.07.24
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention provides a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof which has an excellent NHE3 inhibitory effect: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ[Formula 15]€ƒ€ƒ€ƒ€ƒ€ƒA-Y [1] wherein A represents a structure represented by the following formula [2]: wherein R 11 and R 12 each represent a halogen atom or the like, R 2 represents C 1-6 alkyl or the like, ring E represents triazole, tetrazole, pyrimidine, or the like, R 31 and R 32 each represent a hydrogen atom, C 1-6 alkyl, C 1-6 alkoxy, or the like, and W represents a single bond, the formula -NH-, the formula -O-, or the formula -CONH-, and Y represents a hydrogen atom or a structure represented by the following formula [3']:
来源网站:
中国工程科技知识中心
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