A submicron emulsion of paclitaxel using steroid complex as intermediate carrier

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专利权人:

Institute of Mataria Medica; Chinese Academy of Medical Sciences

发明人:

Liu, Yuling,Xia, Xuejun,Guo, Ruifang,Zhang, Pengxiao,Han, Rui,Fu, Zhaodi,Zhou, Cuiping,Wang, Renyun,Jin, Dujia

申请号：

AU2010312021

公开号：

AU2010312021B2

申请日:

2010.10.28

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

A submicro emulsion of paclitaxel, the preparation method and the use thereof are disclosed. Said submicro emulsion comprises a paclitaxel-steroid complex, oil for injection, water for injection, an emulsifier, a co-emulsifier and a isotonizing agent, wherein the mole ratio of paclitaxel to steroid in the complex is 1: 0.2-4, preferably 1: 0.25-2. Said submicro emulsion is useful for the treatment of malignant tumor. The particle size of the emulsion is less than 400 nm and the pH value is 3.5-6.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/