A submicron emulsion of paclitaxel using steroid complex as intermediate carrier

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专利权人:

Institute of Mataria Medica; Chinese Academy of Medical Sciences

发明人:

Liu, Yuling,Xia, Xuejun,Guo, Ruifang,Zhang, Pengxiao,Han, Rui,Fu, Zhaodi,Zhou, Cuiping,Wang, Renyun,Jin, Dujia

申请号：

AU2016210620

公开号：

AU2016210620A1

申请日:

2016.08.02

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2016210620A120160818.pdf#####Abstracts A submicron emulsion of paclitaxel, the preparation method and the use thereof are disclosed. Said paclitaxel submicron emulsion comprises paclitaxel/steroid complex, oil for injection, water for injection, emulsifier, assistant emulsifier and isotonic agent, wherein the mole ratio of paclitaxel to steroid in the complex is 1:0.2-4； preferably 1:0.25-2. Said submicron emulsion is useful for the treatment for malignant tumor. The average particle diameter of the submicron emulsion is less than 400 nm and the pH Value is 3.5-6.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/