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Block-shaped scaffold for tissue engineering and production method thereof
专利权人:
Katsushi Yamamoto
发明人:
Katsushi Yamamoto,Katsuyuki Yamanaka,Youko Suda,Tadashi Kaneko
申请号:
US12488862
公开号:
US08518432B2
申请日:
2009.06.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A block-shaped scaffold for a tissue engineering with improved shape stability and less volume change in water is produce by the steps of approximate-uniformly mixing the particle-shaped material having 100 to 2000 μm diameter with a solution, where a biodegradable polymer is dissolved with an organic solvent, freezing, drying it to remove the solvent, pulverizing thus obtained intermediate product, dissolving it with a liquid, where the biodegradable polymer is not dissolved, to remove the particle-shaped material taking thus obtained intermediate product into a mold, and pressing and heating it, the scaffold having ununiform and continuous holes occupying 20 to 80% in a cross-section area in a three-dimensional network structure having a small hole structure with 5 to 50 μm diameter, elastic coefficient being 0.1 to 2.5 MPa, and volume change being 95 to 105% when dipping it in water for 24 hours.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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