The present invention provides compositions and methods for inducingmaturation of immature dendritic cells (DC) and for priming those cells forinducing a type 1 immune response. The present invention also providesdendritic cell populations useful for activating and for preparing T cellspolarized towards production of type 1 cytokines and/or a type 1 response.Similarly, activated, polarized T cell populations, and methods of making thesame are provided.