A wound treatment apparatus (10) includes a negative pressure source (12), a bandage (22) configured to cover a wound and provide a sealed region around the wound, a drainage tube (21) coupled to the bandage (22) and the negative pressure source (12) to drain fluid from the wound. The apparatus (10) also includes a controller (14) coupled to the negative pressure source (12) and at least one of an oxygen sensor (26), a carbon dioxide sensor (30), a pH sensor (28), and a temperature sensor (29) in fluid communication with the drainage tube (26).