BLÄTTLER, Walter,ROMÃO, Carlos,RODRIGUES, Sandra,KROMER, Lukas,OTTERBEIN, Leo,GALLO, David
申请号：
ES12774004
公开号：
ES2656237T3
申请日:
2012.04.19
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A compound of Formula (I): ** (See formula) ** or a salt, an ester, an amide, a solvate or a hydrate thereof, or a combination thereof, in which: each case of R1 it is independently hydrogen, an unsubstituted C1-3 alkyl or a C1-3 alkyl substituted with - CO2RA1 or -C (>； = O) N (RA1) 2, wherein each case of RA1 is independently hydrogen or C1-10 alkyl； each case of R2 is independently hydrogen, an unsubstituted C1-3 alkyl or a C1-3 alkyl substituted with - CO2RA2 or -C (>； = O) N (RA2) 2, where each case of RA2 is independently hydrogen or alkyl C1-10； or R1 and R2 and the carbon to which they are both bonded independently to form a C3-4 carbocyclyl； with the proviso that each case of R1 and R2 attached to the same carbon is not hydrogen； wherein an ester of a compound of Formula (I) is a compound in which one or more acid hydrogen atoms of the carboxylic acid groups in the molecule are replaced with a C1-10 alkyl group； and an amide of a compound of Formula (I) is a compound in which one or more of the -OH groups of the carboxylic acid groups in the molecule are replaced with an amino group, C1-10 amino alkyl or C1-dialkyl- 10 aminoUn compuesto de la Fórmula (I): **(Ver fórmula)** o una sal, un éster, una amida, un solvato o un hidrato del mismo, o una combinación de los mismos, en la que: cada caso de R1 es independientemente hidrógeno, un alquilo C1-3 sin sustituir o un alquilo C1-3 sustituido con - CO2RA1 o -C(>；=O)N(RA1)2, en donde cada caso de RA1 es independientemente hidrógeno o alquilo C1-10； cada caso de R2 es independientemente hidrógeno, un alquilo C1-3 sin sustituir o un alquilo C1-3 sustituido con - CO2RA2 o -C(>；=O)N(RA2)2, en donde cada caso de RA2 es independientemente hidrógeno o alquilo C1-10； o R1 y R2 y el carbono al que están unidos ambos se unen independientemente para formar un carbociclilo C3-4； con la condición de que cada caso de R1 y R2 unidos al mismo carbono no sea ninguno hidrógeno； en donde un éster de un compuesto de Fórmula
