THE GEORGE WASHINGTON UNIVERSITY; A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION
发明人:
CHAWLA, LAKHMIR
申请号:
RSP20200021
公开号:
RS59804B1
申请日:
2014.12.18
申请国别(地区):
RS
年份:
2020
代理人:
摘要:
The present invention relates,inter alia,to a method comprising administering to a subject having high output shock and undergoing treatment with a catecholamine at a dose equivalent to at least about 0.2 mcg/kg/min of norepinephrine a dose of angiotensin II which is effective to raise the blood pressure of the subject to a mean arterial pressure (MAP) of about 65 mm Hg or above, and which is effective to reduce the dose of the catecholamine required to maintain a MAP of about 65 mm Hg to the equivalent of about 0.05-0.2 mcg/kg/min norepinephrine or less, or to the equivalent of about 0.05 mcg/kg/min norepinephrine or less.