A pressurized medical instrument may include a piston handle system, a locking release system and a pressure display system. The piston handle system may include a piston, a piston seal, a handle and a rear cover. The locking release system may include a push button, a fixed support, a locking block, one or more springs and a slide block. The pressure display system may include a coating, a gauge stand, a lateral board, a gauge stand seal ring, a pressure gauge seal ring, a snapper, a pressure gauge and a rotary Luer conical tapered fitting. The pressurized medical instrument may facilitate rapid boosting operation by two hands, vacuum pumping by two hands and rapid pressure relief by a single hand. The instrument is characterized by ease-of-operation, quick boosting and pressure relief for observing easily the pressure value at different operating angles.