The present invention discloses therapeutic compositions and methods for treating a patient having a tumor disease. Methods, and dietary compositions thereof, for determining a diet regime for a patient with a tumor disease include the steps of: providing a sample of the patient profiling at least one biochemical parameter of the sample using a biochemical analyzer to obtain a profile identifying a biologically-active molecular feature of the profile correlating the feature with a biochemical pathway related to the tumors metabolism or proliferation determining the diet regime specific to the patient, wherein the diet regime includes at least one biologically-active molecule corresponding to the feature of the profile and administering the diet regime to the patient in a therapeutically-effective dosage. Preferably, the sample is selected from the group consisting of: a tumor sample, biological tissue, an organ sample, blood, blood serum, blood plasma, and urine.