THE METHODS FOR TREATMENT OF TUMORS

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专利权人:

THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人:

EARP, Henry Shelton, III

申请号：

WO2016US56040

公开号：

WO2017062797(A1)

申请日:

2016.10.07

申请国别(地区):

世界知识产权组织国际局

年份:

2017

代理人:

摘要：

This invention is in the area of improved therapeutic combinations for and methods of treating selected cancers using specific Mer tyrosine kinase (MerTK) inhibitors in combination with immune checkpoint inhibitors. In one aspect, an improved treatment for select cancers is disclosed using specific Mer tyrosine kinase (MerTK) inhibitors, for example UNC2371, in combination with an immune checkpoint inhibitor, for example, a cytotoxic T-lymphocyte-associated protein 4 (CTLA4) inhibitor, a programmed cell death protein 1 (PD1) inhibitor, or a programmed death-ligand 1 (PDL-1) inhibitor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/