Methods for multi-user MIMO co-scheduling with interference measurement are disclosed. A method includes: transmitting a first RS to a UE; receiving a first CSI feedback from the UE as the UE measures the first RS; transmitting initial co-scheduling information and a second RS to the UE, the initial co-scheduling comprising an identifier of at least one co-scheduled object that is to use the same time-frequency resource as the UE by Spatial Multiplexing (SM) in the data transmission, the initial co-scheduling information being derived based on the first CSI; receiving a second CSI feedback from the UE as the UE measures the second RS at least based on the initial co-scheduling information, the second CSI comprising an indication of an interference level from at least one co-scheduled object; and adjusting the initial co-scheduling information according to the second CSI to obtain refined co-scheduling information. The method can be applied to Full-Dimension MIMO. Associated base stations and UEs are also disc