Hydrochloride salt of ((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino] -7H-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

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专利权人:

Millennium Pharmaceuticals; Inc.

发明人:

Armitage, Ian G.,Chopra, Reenu,Cooper, Martin Ian,Langston, Marianne

申请号：

AU2013204831

公开号：

AU2013204831A1

申请日:

2013.04.12

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013204831A120130509.pdf#####H:\SXD\Intenvoven\NRPorlbl\DCC\SXD\5072063_I.doc-12/04/2013 ABSTRACT Disclosed is a compound of formula (1) crystalline forms thereof, and solvates thereof pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent and the use of a compound of formula (1), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an El activating enzyme, particularly NAE, including, e.g., cancer. NH N aN .. N .HCI H2N HO

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