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Crystal of salt of novel 3-azabicyclo[3.1.0]hexane derivative and pharmaceutical use thereof
专利权人:
SANWA KAGAKU KENKYUSHO CO., LTD.;UBE INDUSTRIES, LTD.
发明人:
Ryo Iwamura,Yasunori Tsuzaki,Hiroyuki Setoguchi,Hiroto Akaza,Yasuhito Yamamoto,Akira Takama,Yuka Kuno
申请号:
US15575188
公开号:
US10392345B2
申请日:
2016.05.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are a crystal comprising a compound, which has μ-opioid receptor antagonistic action, few side effects, and high safety, and having high purity and excellent physical properties (stability, solubility, etc.), and a method for producing the crystal.The crystal is a crystal of a salt comprising: a compound represented by a formula (I)[wherein R2 is a hydrogen atom or a halogen atom, and R1 is a group selected from the group consisting ofand an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, and oxalic acid, or a hydrate thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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