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一種新型的3-氮雜雙環[3.1.0]己烷衍生物的鹽的晶體以及其醫藥應用
专利权人:
SANWA KAGAKU KENKYUSHO CO., LTD.;UBE INDUSTRIES, LTD.;UBE INDUSTRIES, LTD.;宇部興產株式會社
发明人:
IWAMURA Ryo,TSUZAKI Yasunori,SETOGUCHI Hiroyuki,AKAZA Hiroto,YAMAMOTO Yasuhito,TAKAMA Akira,KUNO Yuka,赤座博人,YAMAMOTO Yasuhito,山本康仁,TAKAMA Akira,高間昭,KUNO Yuka,久野祐花
申请号:
HK18106020.1
公开号:
HK1246778A
申请日:
2018.05.09
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
Disclosed herein are a crystal comprising a compound, which has µ-opioid receptor antagonistic action, few side effects, and high safety, and having high purity and excellent physical properties (stability, solubility, etc.), and a method for producing the crystal. The crystal is a crystal of a salt comprising: a compound represented by a formula (I) [wherein R 2 is a hydrogen atom or a halogen atom, and R 1 is a group selected from the group consisting of ]; and an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, and oxalic acid, or a hydrate thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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