KOREA YAKULT CO., LTD.;주식회사한국야쿠르트; LTD.;KOREA YAKULT CO.
发明人:
MYOUNG, KIL SUN,명길선,ANH, YOUNG TAE,안영태,HUH, CHUL SUNG,허철성
申请号：
KR1020110114092
公开号：
KR1020130049056A
申请日:
2011.11.03
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: Lactobacillus johnsonii HY7042 is provided to suppress the proliferation of Gardnerella vaginalis by producing hydrogen peroxide(H2O2), to ensure acid resistance and adhesion to vagina cells, and to treat vaginitis. CONSTITUTION: Lactobacillus johnsonii HY7042(deposit number: KCTC12033BP) suppresses the proliferation of pathogenic bacteria causing vaginitis. The strain ensures acid resistance and adhesion to epithelial cells. The proliferation of the pathogenic bacteria is suppressed by suppressing the inflammation of vagina cells after oral administration. The strain has an excellent hydrogen peroxide generation property. The pathogenic bacteria are Gardnerella vaginalis. A pharmaceutical composition for preventing and treating vaginitis contains the strain as an active ingredient. Fermented milk contains the strain as the active ingredient. A functional beverage contains the strain as the active ingredient. Health functional food contains the strain as the active ingredient. [Reference numerals] (AA) Number of pathogenic bacteria(g)； (BB) Normal； (CC) Pathogenic bacteria administration； (DD) Pathogenic bacteria administration + HY7042 oral administration； (EE) Pathogenic bacteria administration + HY7042 direct administration본 발명은 질염 병원균의 증식을 억제하는 활성을 갖는 신규의 락토바실러스 존소니(Lactobacillus johnsonii) HY7042 및 이를 유효성분으로 함유하는 약학적 조성물, 발효유, 음료 및 건강기능식품에 관한 것으로서, 락토바실러스 존소니(Lactobacillus johnsonii) HY7042는 과산화수소(H2O2)를 생산하여 질염 병원균인 가드너렐라 바지날리스(Gardnerella vaginalis)의 증식을 억제하는 효과가 있으며, 내산성과 질 세포에 부착능력이 뛰어나 경구 섭취 형태로도 여성의 질 내 건강의 유지 및 질염 치료에 효능을 나타낼 수 있다.
