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Methods for modulating bacterial virulence and related compounds
专利权人:
发明人:
Vanessa Sperandio,John R. Falck
申请号:
US14203202
公开号:
US09604946B2
申请日:
2014.03.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to compounds and methods for the treatment of bacterial infections. The compounds and methods involve the disruption of the QseC signaling pathway which modulates the virulence of some bacteria. This methodology for treatment of bacterial infections reduces evolutionary pressure to develop resistance because the bacteria are not killed in the process.
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