The present disclosure relates methods of promoting phase II enzyme gene expression in a pediatric subject, comprising administering to the subject a nutritional composition comprising an effective amount of a phytonutrient. The disclosure also relates to methods of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients. The disclosure further relates to a method of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients.本發明關於促進小兒個體第II期酵素基因表現之方法,其包含投予該個體一種包含有效量的植物營養素之營養組成物。本發明亦關於促進出生前嬰兒第II期酵素基因表現之方法,其包含投予懷有該出生前嬰兒的女性有效量的包含植物營養素之組成物。本發明另關於促進出生前嬰兒第II期酵素基因表現之方法,其包含投予懷有該出生前嬰兒的女性有效量的包含植物營養素之組成物。