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Amine compound and its use for medical purposes
专利权人:
Mitsubishi Tanabe Pharma Corporation
发明人:
HAMADA, Maiko,TASHIRO, Kaoru,SAKASHITA, Hiroshi,KIUCHI, Masatoshi,TAKEDA, Shuzo,ADACHI, Kunitomo
申请号:
ES13781245
公开号:
ES2665336T3
申请日:
2013.04.23
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
An amine compound represented by the following formula (I) ** (See formula) ** wherein R1 is a hydrogen atom or P (>; = O) (OH) 2, V is alkylene having 1-4 carbon atoms or alkenyl having 2-4 carbon atoms, R2 is a hydrogen atom, or alkyl having 1-4 carbon atoms and which is optionally substituted with a hydroxy group or a halogen atom, R3 and R4 are the same or different and each is a hydrogen or alkyl atom that has 1-4 carbon atoms, X and Y are the same or different and each is an oxygen atom, a sulfur atom, methylene, -CO-, -SO-, -SO2- or -NR5- (where R5 is a hydrogen or alkyl atom that has 1-4 carbon atoms and optionally has a substituent (s)), A1 and A2 are the same or different and each is a single bond , an oxygen atom, a sulfur atom, -CO-, - SO-, -SO2- or -NR6- (where R6 is a hydrogen atom, alkyl having 1-6 carbon atoms and that optional Mind has substituent (s), acyl having 1-7 carbon atoms and optionally having substituent (s) or alkoxycarbonyl having 2-7 carbon atoms), B1 and B2 are the same or different and each is a single bond , alkylene having 1-10 carbon atoms and optionally having a substituent (s), alkenylene having 2-10 carbon atoms and optionally having a substituent (s) or alkynylene having 2-10 carbon atoms and optionally having substituent (s), C1 and C2 are the same or different and each is a hydrogen atom, a halogen atom, aryl having 6-10 carbon atoms and optionally having substituent (s), heteroaryl which optionally has substituent ( s) and which has 5 to 10 atoms that constitute the ring, which contains 1 or 2 nitrogen atoms, 1 or 2 oxygen atoms or 1 or 2 sulfur atoms as the atom (s) that constitutes the ring, cycloalkyl that has 3 - 7 carbon atoms and that optionally t It has a substituent (s), which is optionally condensed with benzene which optionally has a substituent (s), or heterocycloalkyl which optionally has a substituent (s) and which has 5 to 7 atoms constituting the ring, containing 1 or 2 nitrogen atoms or 1 or 2 oxygen atoms
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