ALARGOVA ROSSITZA G,BILODEAU MARK T,DUNBAR CRAIG A,KADIYALA SUDHAKAR,SHINDE RAJESH R,LIM SOO PATRICK,SWERYDA KRAWIEC BEATA,WHITE BRIAN H,BAZINET PATRICK ROSAIRE,WOOSTER RICHARD
申请号：
IN201617043274
公开号：
IN201617043274A
申请日:
2016.12.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Nanoparticles and microparticles and pharmaceutical formulations thereof containing conjugates of an active agent such as a therapeutic prophylactic or diagnostic agent attached to a targeting moiety such as a somatostatin receptor binding moiety via a linker have been designed. Such nanoparticles and microparticles can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates the particles and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided for example to treat or prevent cancer or infectious diseases.
