The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various embodiments thereof.In compounds of Formula I, the groups R1, R2, R3, R4, R5, R6and R7have the meaning as described herein. The present invention also provides for methods of using compounds of Formula I and compositions comprising compounds of Formula (I) as DLK inhibitors and for treating neurodegeneration diseases and disorders.本發明提供式(I)化合物及其各種實施例,及包含式(I)化合物及其各種實施例之組合物。在式I化合物中,基團R1、R2、R3、R4、R5、R6及R7具有如本文所闡述之含義。本發明亦提供使用式I化合物及包含式(I)化合物之組合物作為DLK抑制劑及治療神經變性疾病及病症之方法。