A compound of formula (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof, wherein: R1 represents C1-12 alkyl； C2-12 alkenyl, in which the double bond is not adjacent to nitrogen； C3-12 carbocyclyl； -C1-6 alkyl-C3-12 carbocyclic； C3-12 heterocyclyl； -C1-6-heterocyclyl-C3-12 alkyl； C6-12 aryl； C5-12 heteroaryl； - C1-6 alkyl-aryl； -C 1-6 alkyl-C5-12 heteroaryl； -phenyl condensed with C3-12 carbocyclyl or -phenyl condensed with C3-12 heterocyclyl； wherein any of the C3-12 carbocyclyl and C3-12 heterocyclyl groups mentioned above may be optionally substituted with one or more groups selected from methyl and oxo； and wherein any of the aforementioned phenyl, C6-12 aryl and C5-12 heteroaryl groups may be optionally substituted with one or more substituents selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1- haloalkyl 6, C1-6 thioalkyl, -SO2-C1-4alkyl, C1-6 alkoxy, -O-C3-8 cycloalkyl, C3-8 cycloalkyl, -SO2-C3-8 cycloalkyl, C3-6 alkenyloxy, C3- alkyloxy 6-, -C (O) -C 1-6 alkyl, C 1-6 alkoxy-C 1-6 alkyl, nitro, halogen, cyano, hydroxyl, -C (O) OH, -NH 2, -NH-C 1-4 alkyl, -N (C1-4 alkyl) (C1-4 alkyl), -C (O) N (C1-4 alkyl) (C1-4 alkyl), -C (O) NH2, -C (O) NH (C1 alkyl -4), C (O) O-C1-6 alkyl, -SO-C1-4 alkyl and -SO-C3-6 cycloalkyl； or R1 represents phenyl substituted with phenyl, or phenyl substituted with an optionally substituted monocyclic C5-12 heteroaryl group in which any of the aforementioned monocyclic C5-12 heteroaryl groups may be optionally substituted with one or more groups selected from C1 alkyl -4, halogen and C1-4 alkoxy； or R1 represents benzyloxy-substituted phenyl in which any of the aforementioned phenyl or benzyloxy groups may be optionally substituted on the ring with one or more groups selected from C1-4 alkyl, halogen and C1-4 alkoxyUn compuesto de fórmula (I) o una sal, solvato o polimorfo farmacéuticamente aceptable del mismo, incluyendo todos los tautómeros y estereoisómero
