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Kokryštály 5-metyl-2-fenyl-2,4-dihydro-3H-pyrazol-3-ónu a spôsob ich prípravy a použitia
- 专利权人:
- EUROFINS BEL/NOVAMANN S.R.O.
- 发明人:
- VEVERKA MIROSLAV,VEVERKOVA EVA,GALLOVIC JAN
- 申请号：
- SK512011
- 公开号：
- SK512011A3
- 申请日:
- 2011.06.09
- 申请国别(地区):
- SK
- 年份:
- 2013
- 代理人:
- 摘要：
- The invention relates to co-crystals of 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-oneand co-crystallization partners selectednutraceuticals, such as quercetin, gallic acid,chlorogenic acid, 1,3,5-benzenetricarboxylic acid, 3,4-dihydroxybenzoic acid,taurine, vitamins such as nicotinamide and ascorbic acid, acidadipic, citric acid, tartaric acid, acidcamphor-10-sulfonic acid, glycolic acid, aspartic acid,3-oxo-4,7,7-trimethyl-2-oxabicyclo [2.2.1] heptane-1-acidcarboxylic acid hydroquinone sulfonic acid5-sulfosalicylic acid, acid 3-sulfobenzoic acid, tannic acid, acid-succinic acid, urea,imidazolidinethione, biuref 2-ketoglutaric acid,hydrochlorothiazide, aloxane, 2-hydroxysuccinic acid,4-aminosalicylic acid, ethylenediaminetetraacetic acid,quinic acid, 4-acetamidophenol, folic acid,N (4) - acetylcytosine, lactic acid amide, acetamidine,D-mannitol, D-tocopherol succinate, D-tocopherol palmitate,choline chloride, D-glucose, D-fructose, trehalose, hidantoin,urazole, diacetamide, gluaric acid imide, glutaric acid,2-imidazolidinone, caffeine, 1,2-benzisothiazole-3 (2i) -on- (1,1-dioxide), pyrrolidine-5-carboxylic acid, acidL-glutamic acid, N-acetyl-L-glutamic acid, L-carnitine,lactic acid, caffeic acid, ferulic acid, acid3,3'-thiodipropionic acid, coenzyme Q10, acidkoji, 2-methoxyisophthalic acid, maleic acid,L-lysine, donepezil. The invention also relates to a method of preparationthese co-crystals as well as their use as therapeutic agentspurposes and the preparation of medicinal products.Vynález sa týka kokryštálov 5-methyl-2-fenyl-2,4-dihydro3H-pyrazol-3-ónua ko-kryštalizačných partnerov vybranýchzo skupiny nutraceutík, ako sú kvercetin, kyselina gálová,kyselina chlorogenová, kyselina 1,3,5-benzéntrikarboxylová, kyselina 3,4- dihydroxybenzoová,taurín, vitamíny ako nikotínamid a kyselina askorbová, kyselinaadipová, kyselina citrónová, kyselina vínna, kyselinakamfor-10-sulfónová, kyselina glykolová, k
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
