SON, JIN RYUL,BAEK, HYON HO,PARK, EUN HEE,LEE, SUNG WAN,SONG, MIN GYU,CHA, JA HYUN,CHA, JAE UK,KO, WON HWA
申请号：
EP11792597
公开号：
EP2579853A4
申请日:
2011.02.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
A method of preparing enteric hard capsules, and an enteric hard capsule prepared by the method. The method may include: dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water at room temperature to prepare an aqueous composition； heating the aqueous composition to a first temperature that is higher than a gelation start temperature of the aqueous composition； cooling the heated aqueous composition to a second temperature that is lower than the gelation start temperature； immersing a mold pin heated to a third temperature that is higher than the gelation start temperature into the aqueous composition； removing the mold pin from the aqueous composition to obtain a film coated on the mold pin； maintaining the film on the mold pin at a fourth temperature that is higher than the gelation start temperature for a first time period to fix the film onto the mold pin； and drying the fixed film at a fifth temperature for a second time period to obtain a capsule shell.
