COMPOSITION CONTENANT COMME PRINCIPE ACTIF DES EXOSOMES DÉRIVÉS DE CELLULES SOUCHES ADIPEUSES POUR LA PRÉVENTION OU LE TRAITEMENT DE LA FIBROSE HÉPATIQUE
The present invention relates to a composition containing human adipose stem cell-derived exosomes as an active ingredient for preventing, alleviating or treating liver fibrosis. The adipose stem cell-derived exosomes according to the present invention carry genetic information, protein, growth factor and the like for treating liver fibrosis, and have shown excellent results in treating liver fibrosis in animal models therefor, and, being a cell-derived substance, exosomes have the advantages of being highly biocompatible and having a superb absorption rate. Accordingly, the limits of medicine in current use or adverse reactions that can arise due to cancerization of stem cells or cell waste products in treatments using stem cells themselves can be minimized, and the delivery to the liver can be natural via intravenous injection, local injection and the like which can be applied simply without surgery, thus economic cost can be reduced and stress on the patient can also be lessened. In conclusion, the adipose stem cell-derived exosomes according to the present invention are expected to be effectively used for preventing, alleviating and treating liver fibrosis.
