CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA
发明人:
DUAN, WENHU,DING, JIAN,LV, YONGCONG,XIE, HUA
申请号:
CA2940614
公开号:
CA2940614A1
申请日:
2015.02.15
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis.