Chinese Academy of Sciences;Shanghai Institute of Materia Medica
发明人:
Duan, Wenhu,Ding, Jian,Lv, Yongcong,Xie, Hua
申请号:
AU2015221343
公开号:
AU2015221343A1
申请日:
2015.02.15
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis.