Naphthylamide compounds, their production and use

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专利权人:

インスティテュート;マテリア;上海;アカデミー;メディカ、チャイニーズ;オブ;サイエンシーズ

发明人:

ダン，ウェンフウ,ディン，ジャン,リュウ，ヨントン,シエ，ファ,ダン,ウェンフウ,ディン,ジャン,リュウ,ヨントン,シエ,ファ

申请号：

JP2016570154

公开号：

JP6353556B2

申请日:

2015.02.15

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis.

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