THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;ALBANY MOLECULAR RESEARCH, INC.
发明人:
申请号：
EP08833236.6
公开号：
EP2215074B1
申请日:
2008.09.26
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
Disclosed is a compound of Formula I in which W and R 1 -R 6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced directly or indirectly by mutation or frameshift.
