GALLOP, MARK A.,YAO, FENMEI,LUDWIKOW, MARIA J.,PHAN, THU,PENG, GE
申请号：
CA2536257
公开号：
CA2536257C
申请日:
2004.08.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of(.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof,pharmaceutical compositions thereof , methods of making prodrugs of (.plusmn.)4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, methods of usingprodrugs of (.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogsthereof, and pharmaceutical compositions thereof for treating or preventingcommon diseases and/or disorders such as spasticity and/or acid refluxdisease. The disclosures herein also relate to acyloxyalkyl carbamate prodrugsof (.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereofwhich are suitable for oral administration and to sustained release oraldosage forms thereof.
