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5,6-DIHYDRO-11H-INDOLO[2,3-B]QUINOLIN-11-ONES AS ALK INHIBITORS
专利权人:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
Jianyong Chen,Liu Liu,Xuyuan Dong,Chao-Yie Yang,Donna McEachern,Shaomeng Wang
申请号:
US16347630
公开号:
US20190315741A1
申请日:
2017.11.17
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure provides compounds represented by Formula (I), and the pharmaceutically acceptable salts and solvates thereof wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.and (R)
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