FOLEY MEGAN ALENE CLOONAN,KUNTZ KEVIN WAYNE,MILLS JAMES EDWARD JOHN,MITCHELL LORNA HELEN,MUNCHHOF MICHAEL JOHN,HARVEY DARREN MARTIN
申请号：
IN201737008515
公开号：
IN201737008515A
申请日:
2017.03.10
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present disclosure provides carboxamides and sulfonamides having Formula (I): and the pharmaceutically acceptable salts and solvates thereof wherein A Y B X and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.
